Ingredients/Content

Of 1 tablet, polyoxetine dapoxetine 60mg

Efficacy/Effectiveness

The premature ejaculation is a common sexual function-related male disease that is always or almost always within a minute of vaginal insertion, and refers to cases of mental pain or influence, such as the inability to delay the ejaculation, and avoiding sexual relationships due to stress and frustration. Based on research results that show that the concentration of serotonin, a neurotransmitter, may decrease in the area in charge of ejaculation of the brain, drugs that increase the concentration of serotonin are used as oral premature ejaculation.

Dafoxetin is a drug of the selective serotonin reuptake inhibitor (SSRI) family that treats premature ejaculation by increasing the concentration of serotonin in the central nervous system. The nerve cells in the brain are connected to each other through a structure called synapse, and the signal is transmitted by binding the neurotransmitter secreted from the ends of the nerve cells to the receptors of the opposite nerve cells. The neurotransmitter secreted from the ends of the nerve cells is lowered in concentration by reabsorption, and selective serotonin reuptake blockers such as polyfoxetin increase the serotonin concentration in the synapse by blocking the reuptake of serotonin, thereby increasing the action. Unlike other selective serotonin reuptake blockers generally used to treat depression, Dafoxetin is used as an oral premature ejaculation because it is rapidly absorbed and discharged in the body.

Sexual function-related drugs on the market in Korea are designated and managed by the Ministry of Food and Drug Safety as drugs of concern for misuse in order to prevent them from being misused socially, unlike the originally approved purpose of treatment. Dafoxetine is also designated as a drug of concern for misuse due to the difficulty of distinguishing between erectile dysfunction and premature ejaculation, and must be used under the guidance of an expert.

Usage/Capacity

30-60 mg approximately 1 to 3 hours prior to sexual activity (first dose can be increased to 30 mg, if not sufficient, up to 60 mg)

It is administered regardless of the meal. It can only be administered once within 24 hours.

Precautions for use

It is not administered to patients with pathologically serious heart disease (heart failure, serious valve disease, etc.).

It is not administered to patients with moderate and severe liver disorders.

It is not administered to patients receiving MAO inhibitors or to patients within 14 days after stopping MAO inhibitor administration. MAO inhibitors should not be administered within 7 days after stopping polyoxetine administration.

It should not be used in combination with serotonin-like drugs and biopharmaceuticals, and is not administered to patients within 14 days after discontinuation of administration. These drugs should not be administered within 7 days after discontinuation of dapoxetin administration.

Some potent hepatic metabolic enzyme inhibitors (ketoconazole, itraconazole, ritonavir, saquinavir, etc.) are not administered to patients who are being administered.

It can cause orthostatic hypotension (hypertension caused by postural changes, such as lying down or sitting), so do not administer it if you have a history of orthostatic reactions or have similar reactions in orthostatic tests (blood pressure, pulse, lying, standing up).

Patients with major psychiatric disorders such as depression, anxiety disorders, suicidal tendencies, and schizophrenia have no clinical experience and cannot be excluded from the possibility of worsening symptoms, so they are not administered.

It is not administered to women, children and adolescents under the age of 18 and to older adults over 65.

Side effects

Side effects include increased facial and body heat, blood clots in the eyes, and good blood circulation due to vasodilation. There have also been reports of dizziness and indigestion due to headaches, wintering, and decreased blood pressure. It is also said that symptoms include nasal congestion, visual impairment, excitement, insomnia, and diarrhea.

Expiration date

We send you the longest product among the products you have.

Packaging unit

100T

Storage method

Store at room temperature (1-30℃), shielded airtight container

etc

It is recommended to consult a doctor before personal income to gain sufficient knowledge of the drug. This product is prohibited for minors, women, and people with other diseases.

Manufacturer

Healing Pharma