Product descriptions

Dapagliflozin is a prescription drug used primarily in combination with diet and exercise to help treat type 2 diabetes, but it is also used to treat heart failure. It was approved by the Food and Drug Administration (FDA) in 2014.

Dapagliflozin은 sodium-glucose cotransporter 2 (SGLT2) 억제제입니다.

This kind of drug helps to control glucose (blood sugar) levels using the kidneys.

Increasing the amount of glucose removed from the body when urinating is working.

It also reduces the amount of effort the heart must put into pumping blood around the body.

In addition, Posigam can be helpful for weight loss in that the SGLT-2 inhibitor has nothing to do with insulin secretion. The low risk of hypoglycemia is the major advantage of the drug.

An active ingredient

5mg of dapagliflozin per tablet

Efficacy/Effectiveness

Improve glycemic control in type 2 diabetes patients and reduce the risk of heart failure hospitalization in adults with type 2 diabetes and known cardiovascular disease.

(including high blood pressure, high cholesterol, and smokers). Dapagliflozin, along with other SGLT2 inhibitors, has been shown to reduce the incidence of decreased renal function and renal failure in adults with non-diabetic and type 2 diabetes.

Dapagliflozin is also considered an option for patients with type 2 diabetes and heart failure with LVEF less than 40%. It can be given regardless of current.

Recent studies have shown that the use of other drugs in the SGLT-2 inhibitor family, such as dapagliflozin and empagliflozin, can worsen HF or reduce the risk of death and hospitalization from CVD.

Although all SGLT-2 inhibitors are useful for reducing the risk of heart failure hospitalization in patients with atherosclerotic cardiovascular disease

A handful of meta-analysis and cohort studies have shown that dapagliflozin is superior to other drugs such as empagliflozin.

How to take it

Make sure to follow the instructions on how to take the medication instructions.

Usually, adults administer 5MG (0.5 tablets) once a day orally as dapagliflozin.

In addition, if the effect is insufficient, it can be increased once a day with sufficient observation of the progress.

If you forget to take it, skip 1 dose and take 1 dose at the next dose. Never take 2 doses at once.

Precautions for use

The following patients cannot be administered.

1) Patients who have a history of hypersensitivity to the main ingredient or additives of this drug

2) Type 1 diabetic or diabetic ketoacidosis patients

3) This drug contains lactose anhydride. It should not be administered to patients with genetic problems such as galactose intolerant lactase deficiency or glucose-galactose malabsorption

4) a patient on dialysis

Side effects

Because sugar is excreted directly in the urine, it can make you vulnerable to infection.

As a result, you can be vulnerable to genital and urinary infections such as cystitis, urinary tract infections, and genital fungal infections, so you need to pay more attention to hygiene management.

When taking it, you must consider whether there are any abnormalities in liver or kidney function.

(Because it plays the biggest role in metabolism, detoxification, and discharge)

In the case of severe liver disorder, it is prescribed by reducing it to 5mg, and in the case of renal disorder, if the glomerular filtration rate is less than 45, it is not usually reduced and used, and it is not usually prescribed itself, so taking it is prohibited for dialysis patients.

Storage method

Store at room temperature (1-30℃), shielded airtight container

Manufacturer

SUN PHARMA