Ingredients/Content

1 tablet Rosuvastatin 5mg 

Description

Crestor 5 MG Tablet is a statin drug sold under the product name Crestor and is used to prevent high-risk cardiovascular disease and treat lipid abnormalities. It is recommended for use with diet improvement, exercise, and weight loss and is for oral use. 

Rosubastatin was patented in 1991 and was recognized as a dosable drug in the United States in 2003. It can be manufactured as a generic medication. In 2018, it ranks 29th in the number of prescriptions in the United States with more than 34 million prescriptions.

Efficacy/Effectiveness

Rosuvastatin is mainly used to prevent cardiovascular disease and treat lipid dysplasia.

The effect of rosuvastatin on LDL cholesterol (low-density lipoprotein, LDL) is associated with medication. Rosuvastatin is more effective in improving lipid profile in hypercholesterolemia patients than atovastatin at milligram levels, simvastatin at milligram levels, and pravastatin at milligram levels or higher.

Meta-analysis reports that rosuvastatin, like other statins, moderately increases high-density lipoprotein (HDL) cholesterol levels. In 2014, a Cochrane review proved that rosuvastatin continues to lower non-HDL cholesterol levels through administration. HDL cholesterol increases to 7% in the absence of any effect.

Packaging unit 

300 pieces per box

Side effects

Common side effects are abdominal pain, nausea, headache, and muscle pain. Serious side effects include rhabdomyolysis, liver problem, and diabetes. It can have a bad effect on the fetus when taken during pregnancy. Like other statins, rosuvastatin has the effect of inhibiting HMG-CoA reductase, an enzyme that produces cholesterol in the liver.

Several contraindications and symptoms to stop treatment for rosuvastatin are hypersensitivity, active liver disease, elevated serum transaminase, pregnancy, and lactation. Rosuvastatin should not be taken during pregnancy because it can cause serious injury to the fetus. It is not known whether rosuvastatin flows into breast milk, but it should not be lactated during rosuvastatin due to the possibility of harming lipid metabolism in infants.

In the United States, the risk of muscle disease is high among Asian Americans. Asians prescribe different drugs, so only half of the standard dose can benefit from lowering cholesterol in patients, but according to a study by pharmaceutical company AstraZeneca, an entire standard dose may increase the risk of side effects. Therefore, the lowest dose is recommended for Asians.

Storage method

Store at room temperature (1-30℃), shielded airtight container

Manufacturer

AstraZeneca